Human GPT (1-496) protein, His Tag

SKU: orb3158034

Description

This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 56.5 kDa. The protein migrates as 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Key Properties

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Expression System	E. coli
Target	GPT
Reactivity	Human
Tag	C-10×His
Molecular Weight	56.5 kDa
Expression Region	Met 1 - Ser 496
Purity	85%
Conjugation	Unconjugated

Storage & Handling

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Storage	-70°C
Form/Appearance	Liquid
Buffer/Preservatives	20 mM Tris, 0.5 M Arginine, 0.5 M NaCl, pH 8.0
Expiration Date	6 months from date of receipt.
Dry Ice Shipping	Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

GPT

UniProt

P24298

RefSeq:P24298

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	P24298

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