Human MAOA Protein

SKU: orb1496122

Description

MAOA, Monoamine oxidase-A is an FAD-dependent mitochondrial enzyme, which, together with its isoenzyme MAO-B, catalyses the oxidative deamination of structurally diverse amines. MAOA is mainly involved in the metabolism of monoamine neurotransmitters, such as such as serotonin, dopamine, and norepinephrine. Inhibitors of MAOA are in clinical use for affective disorders and is approved to treat despression.

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 61.6 kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE).

Key Properties

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Source	Human MAOA, His Tag (orb1496122) is expressed from Baculovirus-Insect cells. It contains AA Glu 2 - Ser 527 (Accession # P21397-1).
Expression System	InsectCells
Target	MAOA
Reactivity	Human
Tag	N-10×His
Molecular Weight	61.6 kDa
Expression Region	Glu 2 - Ser 527
Purity	95%
Endotoxins	0.01 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-70℃
Form/Appearance	Liquid
Buffer/Preservatives	50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Expiration Date	6 months from date of receipt.
Dry Ice Shipping	Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

MAOA

UniProt

P21397

RefSeq:P21397

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	P21397

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