Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Hydroxy-α-sanshool

SKU: orb1685390

Description

Hydroxy-α-sanshool is a natural alkylamide from Szechuan pepper, functioning as a dual agonist for TRPA1 (covalent, EC50 69 µM) and TRPV1 (non-covalent, EC50 1.1 µM). It is a valuable research tool for studying somatosensation, pain mechanisms, and the pharmacological modulation of these ion channels in both cellular and animal models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number83883-10-7
MW263.38
Purity99.47% (May vary between batches)
FormulaC16H25NO2
SMILESC\C=C\C=C\C=C/CC\C=C\C(=O)NCC(C)(C)O
TargetEndogenous Metabolite,TRP/TRPV Channel
SolubilityDMSO:37.5 mg/mL (142.38 mM);10% DMSO+90% Corn Oil:2 mg/mL (7.59 mM)

Bioactivity

Target IC50
TRPA1:69 µM (EC50)|TRPV1:1.1 µM (EC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Endogenous Metabolite, EndogenousMetabolite, Inhibitor, Hydroxyαsanshool, Hydroxy-α-sanshool, Hydroxy α sanshool, Hydroxy-​α-​sanshool, Hydroxy-alpha-sanshool, Hydroxy-a-sanshool, inhibit, Transient receptor potential channels, TRP Channel, TRPA1, TRPChannel, TRPV Channel, TRPVChannel, TRPV1
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 210.00
1 ml x 10 mM (in DMSO)
$ 220.00
10 mg
$ 310.00
25 mg
$ 490.00
50 mg
$ 690.00
100 mg
$ 930.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry