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Ibudilast

SKU: orb1224888

Description

Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor which has been marketed for treating asthma.

Images & Validation

Key Properties

CAS Number50847-11-5
MW230.51
Purity>98% (HPLC)
FormulaC14H18N2O
SMILESCC(C)C(C1=C2C=CC=CN2N=C1C(C)C)=O
TargetPDE
SolubilityDMSO: 28 mg/mL; 100 mM in Ethanol

Bioactivity

In Vitro
Western blot analysis. Cell line: Microglia. Concentration: 1~100 μM. Incubation time: 24 hours. Result: Suppressed both IL-1β and IL-6 production at 100 μM, and significantly suppresses TNF-α production at 10 and 100 μM.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AV 411 | KC-404

Similar Products

  • Ibudilast [orb1306386]

    >99.99% (May vary between batches)

    50847-11-5

    230.31

    C14H18N2O

    1 ml x 10 mM (in DMSO), 25 mg, 10 mg, 50 mg, 100 mg, 200 mg
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Ibudilast (orb1224888)

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Available Sizes

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500 mg
10 mg
$ 80.00
25 mg
$ 90.00
50 mg
$ 100.00
100 mg
$ 130.00
200 mg
$ 160.00