Cart summary

You have no items in your shopping cart.

IDH1 Inhibitor 3

SKU: orb1709445

Description

IDH1 Inhibitor 3 is a potent and selective small molecule targeting the mutant IDH1-R132H enzyme, demonstrating an IC50 of 45 nM. It is a valuable research tool for investigating oncogenic metabolism in cancers like glioma and AML, applicable in both cellular assays and in vivo model studies.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2171081-24-4
MW591.56
FormulaC31H25F4N5O3
SMILESN(C(=O)[C@@H]1N(C(=O)CC1)C2=CC(C#N)=CC=N2)([C@]3(C(NC4CC(F)(F)C4)=O)C=5C(CC3)=CC=CC5)C6=CC(F)=CC(F)=C6
TargetIsocitrate Dehydrogenase (IDH),Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • Mutant IDH1-IN-3 [orb2945716]

    1648909-73-2

    366.5

    C22H30N4O

    50 mg, 10 mg
  • IDH1 Inhibitor 1 [orb1709444]

    2234285-81-3

    450.39

    C20H18F4N6O2

    50 mg, 100 mg, 25 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

IDH1 Inhibitor 3 (orb1709445)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%