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IGF1R / CD221 Antibody
SKU: orb1410539
Description
Images & Validation
−Item 1 of 5
| Tested Applications | FC, IF |
|---|---|
| Reactivity | Human |
Key Properties
−| Host | Mouse |
|---|---|
| Clonality | Monoclonal |
| Isotype | IgG2c |
| Clone No. | IGF1R/4667 |
| Immunogen | Recombinant fragment (around aa550-750) of human IGF1R protein (exact sequence is proprietary) |
| Target | IGF1R |
| Source/Expression System | Bioreactor |
| Molecular Weight | 130kDa (IGF-1R); 97kDa (IGF-1R); 200kDa (pro-IGF-1R) |
| Purification | Protein A/G |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml. |
| Disclaimer | For research use only |
Alternative Names
−CD221 antigen; IGF 1 receptor; IGF 1R; IGFIR; IGFIRC; IGFR; Insulin like growth factor 1 receptor precursor; Insulin-like growth factor 1 receptor beta chain; JTK13; Soluble IGF1R variant 1; Soluble IGF1R variant 2
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Analysis of Protein Array containing more than 19000 full-length human proteins using CD221 / IGF1R Mouse Monoclonal Antibody (IGF1R/4667). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Formalin-fixed, paraffin-embedded human breast carcinoma stained with IGF-1R / CD221 Mouse Monoclonal Antibody (IGF1R/4667).
Formalin-fixed, paraffin-embedded human colon carcinoma stained with IGF-1R / CD221 Mouse Monoclonal Antibody (IGF1R/4667).
Formalin-fixed, paraffin-embedded human prostate carcinoma stained with IGF-1R / CD221 Mouse Monoclonal Antibody (IGF1R/4667).
SDS-PAGE Analysis of Purified IGF-1R / CD221 Mouse Monoclonal Antibody (IGF1R/4667). Confirmation of Purity and Integrity of Antibody.
Quick Database Links
Gene Symbol
IGF1R
UniProt
UniProt Details
− No UniProt data available
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Protocol Information
FC
Flow Cytometry
IF
Immunofluorescence
IGF1R / CD221 Antibody (orb1410539)
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