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IL-17-IN-3

SKU: orb2945592

Description

IL-17-IN-3 (compound 11) is a potent small molecule inhibitor of IL-17A, demonstrating an IC50 of 35 nM. It has shown good tolerability in a rat model at doses up to 300 mg/kg/day for four days, supporting its utility for investigating IL-17-mediated pathways in both cellular and animal studies of autoimmune diseases.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

MW553.521
FormulaC22H25F6N5O3S
SMILESC1CC1/C=C(\C(=O)N[C@@H](C2CCC(CC2)(F)F)C(=O)NC3=NC=C(S3)CN4C[C@H](NC4=O)C(F)(F)F)/F
TargetInterleukin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

IL-17-IN-3 (orb2945592)

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