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IL-17A antagonist 1

SKU: orb1709426

Description

This small molecule IL-17A antagonist is a research tool for investigating interleukin-17A signaling. It is applicable for in vitro assays and in vivo models to study the role of IL-17A in autoimmune, inflammatory, and immune-mediated diseases.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2205034-18-8
MW604.71
Purity99.46%
FormulaC33H41FN6O4
SMILESCN(C)C(=O)CC1(CC(=O)NCCc2ccc(NC(=O)[C@H](Cc3ccccc3F)NC(=O)c3ccnn3C)cc2)CCCC1
TargetIL Receptor,Interleukin
SolubilityDMSO:20 mg/mL (33.07 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.31 mM)

Bioactivity

Target IC50
IL-17A:0.66 μM (Kd)|IL-17A:1.14 nM

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ILReceptor, IL-17A, IL17A antagonist 1, IL-17A antagonist 1, IL Receptor, IL 17A antagonist 1
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Key Properties

No computed properties available.

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Protocol Information

IL-17A antagonist 1 (orb1709426)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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