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IL-2-IN-1

SKU: orb1687856

Description

IL-2-IN-1 is a small molecule inhibitor of Interleukin-2 (IL-2) that exhibits antiproliferative effects. It is a valuable research tool for investigating immune system dysregulation, applicable in both in vitro assays and in vivo models of autoimmune and inflammatory diseases.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number245747-10-8
MW418.29
Purity99.60% (May vary between batches)
FormulaC17H12F6N4O2
SMILESO=C(NC1=CC=C(C=C1)N2N=C(C=C2C(F)(F)F)C(F)(F)F)C=3C(=NOC3C)C
TargetIL Receptor,Interleukin
SolubilityDMSO:100 mg/mL (239.07 mM)

Bioactivity

Target IC50
GR (human PBMC):340nM|IL-2:1978 nM|GR (rat PBMC):1266 nM
In Vitro
IL-2-IN-1 is a potent inhibitor of IL-2 synthesis, exhibiting anti-proliferative activity against human PBMC and rat PBMC with IC50 values of 340 and 1266 nM, respectively .

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

IL Receptor, IL-2, ILReceptor
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Key Properties

No computed properties available.

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Protocol Information

IL-2-IN-1 (orb1687856)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
$ 80.00
5 mg
$ 140.00
10 mg
$ 200.00
25 mg
$ 350.00
50 mg
$ 540.00
100 mg
$ 690.00
DispatchUsually dispatched within 6-8 weeks
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