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Immuno modulator-1

SKU: orb2278151

Description

Immuno modulator-1 (compound 22) is a potent suppressor of TNFα (IC50=4.7 nM) and IL-2 (IC50=26 nM) secretion in hPBMCs. It shows moderate hERG channel inhibition (20% at 3 µM). This profile supports its research use in immunology and inflammation studies, both in cellular assays and animal models of autoimmune disease.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2757469-20-6
MW582.62
FormulaC32H31FN6O4
SMILESO(CC1=CC=C([C@@H](C)N2CCN(CC2)C3=C(F)C=C(C#N)C=N3)C=C1)C4=C5C(C(=O)N(C5)[C@@H]6C(=O)NC(=O)CC6)=CC=C4
TargetPotassium Channel,Interleukin,TNF,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

Immuno modulator-1 (orb2278151)

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