Indole-4-carboxaldehyde

SKU: orb1984117

Description

Indole-4-carboxaldehyde (ST-I4C) is a natural small molecule that mitigates methylglyoxal (MGO)-induced inflammatory responses in HepG2 cells. It functions by suppressing advanced glycation end-products (AGEs) and the expression of TNF-α and IFN-γ, while modulating the NF-κB pathway and glyoxalase-1. This compound is a useful research tool for studying oxidative stress, inflammation, and metabolic disorders in cellular models.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	1074-86-8
MW	145.158
Purity	98.89% (May vary between batches)
Formula	C₉H₇NO
SMILES	O=CC1=C2C=CNC2=CC=C1
Target	NF-κB,TNF,COX
Solubility	DMSO:40 mg/mL (275.56 mM)

Storage & Handling

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Storage	store under nitrogen \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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ST I4C, ST-I4C, Indole4carboxaldehyde, Indole-4-carboxaldehyde, Indole 4 carboxaldehyde

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Compound Identifiers

PubChem CID

333703 ↗

Key Properties

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No computed properties available.

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