Interferon alpha Antibody

SKU: orb749586

Description

This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Research Area

Epigenetics

Images & Validation

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Item 1 of 1

Tested Applications	ELISA
Dilution Range	ELISA (order the BSA-free format for coating)
Reactivity	Human
Application Notes	Optimal dilution of the Interferon alpha antibody should be determined by the researcher.1. This clone is also referred to as clone 2-52.

Key Properties

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Antibody Type	Primary Antibody
Host	Mouse
Clonality	Monoclonal
Isotype	Mouse IgG1, kappa
Clone No.	2.52
Immunogen	Purified recombinant human protein was used as the immunogen for the Interferon alpha antibody.
Purification	Protein G affinity chromatography
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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SDS-PAGE Analysis of Purified, BSA-Free Interferon alpha Antibody (clone 2.52). Confirmation of Integrity and Purity of the Antibody.

Quick Database Links

UniProt

P01562

UniProt Details

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No UniProt data available

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Protocol Information

ELISA

Enzyme-linked Immunosorbent Assay (EIA)

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