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Ipsapirone

SKU: orb1704459

Description

Ipsapirone is a 5-HT1A receptor partial agonist that, at elevated concentrations, also inhibits 5-HT2 and α1-adrenergic receptor activity. This pharmacological profile makes it a useful research tool for investigating serotonin and adrenergic systems in both in vitro binding assays and in vivo behavioral models of anxiety and depression.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number95847-70-4
MW401.483
Purity99.51% (May vary between batches)
FormulaC19H23N5O3S
SMILESO=C1N(CCCCN2CCN(CC2)C2=NC=CC=N2)S(=O)(=O)C2=C1C=CC=C2
Target5-HT Receptor
SolubilityDMSO:4.02 mg/mL (10.01 mM)

Bioactivity

In Vivo
Ipsapirone (2.5-80 mg/kg) induces a mild hind limb abduction and a slight flattening of body posture at the highest dose. Ipsapirone (35 mg/kg; i.p.) decreases the body temperature in rats and mice.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Ipsapirone, 5HT Receptor, 5-HT1A, 5HTReceptor

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 70.00
2 mg
$ 80.00
5 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 140.00
25 mg
$ 240.00
50 mg
$ 390.00
100 mg
$ 620.00
200 mg
$ 860.00
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