Isoanhydroicaritin

SKU: orb1684521

Description

Isoanhydroicaritin is a natural flavonoid compound that acts as a tyrosinase inhibitor, suppressing melanin production. It is utilized in biochemical research to study skin pigmentation mechanisms and evaluate potential depigmenting agents in both cellular and enzymatic models.

Research Area

Protein Biochemistry

Images & Validation

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Key Properties

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CAS Number	28610-30-2
MW	368.38
Purity	99.89% (May vary between batches)
Formula	C₂₁H₂₀O₆
SMILES	O=C1C(O)=C(OC=2C1=C(O)C=C(OC)C2CC=C(C)C)C=3C=CC(O)=CC3
Target	Tyrosinase
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.71 mM);DMSO:40 mg/mL (108.58 mM)

Bioactivity

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Target IC50	Mushroom Tyrosinase:0.7 μM
In Vivo	In zebrafish, Isoanhydroicaritin at 80 and 160 μM inhibits physiological melanin biosynthesis by approximately 30%. In a zebrafish depigmentation model, Isoanhydroicaritin at the same doses suppresses pigment regeneration by 33.0% and 34.4%, respectively. Read more...
In Vitro	Isoanhydroicaritin exhibits strong inhibitory activity against mushroom tyrosinase, with an IC₅₀ of 0.7 μM.

Storage & Handling

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Storage	keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Isoanhydroicaritin

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Compound Identifiers

PubChem CID

5322079 ↗

Key Properties

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No computed properties available.

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