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ITK/TRKA-IN-1

SKU: orb1690692

Description

ITK/TRKA-IN-1 is a potent dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA), exhibiting an IC50 of 1.0 nM against ITK and 96% TRKA inhibition. This compound is a valuable research tool for investigating T-cell signaling and neurotrophin pathways in both cellular and animal models of immunology and oncology.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2655557-54-1
MW484.552
FormulaC25H30F2N6O2
SMILES[H][C@]12Cc3c(C[C@@]1(C)C2(F)F)[nH]nc3-c1nc2cc(C)c(cc2[nH]1)N(C)C(=O)[C@H](C)N1CCOCC1
TargetOthers,Tyrosine Kinases

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

ITK/TRKA-IN-1 (orb1690692)

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