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JAK05

SKU: orb2945400

Description

JAK05 is a small molecule inhibitor active against Helicobacter pylori strains (MIC 3-5 µg/mL) with binding affinity for H+/K+-ATPase, COX-1/2, TNF-α, and PGE2. It demonstrates antioxidant, anti-inflammatory, and anti-ulcer properties, validated in vitro and in a rat ethanol-induced gastric ulcer model, supporting research in gastroenterology and infectious disease.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW619.043
FormulaC27H27ClN4O9S
SMILESCC(=O)OC[C@H]1[C@@H]([C@@H]([C@@H]([C@H](O1)N2C(=S)N(C(=N2)C3=CC=NC=C3)C4=CC=C(C=C4)Cl)OC(=O)C)OC(=O)C)OC(=O)C
TargetATPase,Prostaglandin Receptor,TNF,COX,Antibacterial

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

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Protocol Information

JAK05 (orb2945400)

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