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JMV6944

SKU: orb2664600

Description

JMV6944 is a PXR agonist that competitively inhibits the binding of ligands to the ligand-binding domain (LBD) of human PXR, with an IC50 value of 680 nM. Additionally, JMV6944 induces the expression of CYP3A4 mRNA in cultures of freshly isolated primary human hepatocytes.

Images & Validation

Key Properties

CAS Number2871774-93-3
MW518.71
FormulaC30H38N4O2S
SMILESO=S(=O)(NC=1C=CC2=C(N=C(N2CC=3C=CC=CC3)CCCCCCCN)C1)C=4C(=CC(=CC4C)C)C

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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JMV6944 (orb2664600)

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