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JPI-547 HCl

SKU: orb1739525

Description

JPI-547 (NOV 1402) is an orally active dual PARP1/2 and Tankyrase1/2 inhibitor. It exhibits single-agent anti-tumor efficacy in BRCA-deficient models and shows synergistic activity in combination with chemotherapy or immune checkpoint inhibitors in preclinical in vivo studies.

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Key Properties

CAS Number2055357-65-6
MW473.402
FormulaC23H26Cl2N6O
SMILESCl.Cl.O=c1[nH]c2cc(CN3CCN(CC3)c3ccc(cn3)C#N)ccc2c2NCCCc12
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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JPI-547 HCl (orb1739525)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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