Cart summary

You have no items in your shopping cart.

JTE-907

SKU: orb1706000

Description

JTE-907

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number282089-49-0
MW438.47
Purity99.93%
FormulaC24H26N2O6
SMILESCCCCCOc1c(OC)ccc2cc(C(=O)NCc3ccc4OCOc4c3)c(=O)[nH]c12
TargetCannabinoid Receptor
SolubilityDMSO:112.5 mg/mL (256.57 mM)

Bioactivity

In Vitro
JTE 907 acts as a Gq-coupled agonist in islets to stimulate Insulin secretion and maintain β-cell mass in a GPR55-independent fashion. JTE 907 (10 μM) significantly stimulated Insulin secretion from islets isolated from human donors and islets from Gpr55+/+ and Gpr55-/- mice. These stimulatory effects were accompanied by significant elevations of IP1 and [Ca2+ i, but there were no Changes in cAMP generation. JTE 907 also significantly reduced cytokine-induced apoptosis in human and mouse islets and promoted human β-cell proliferation

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

JTE 907, JTE907, JTE-907, CannabinoidReceptor, Cannabinoid Receptor
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

JTE-907 (orb1706000)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 100.00
5 mg
$ 170.00
1 ml x 10 mM (in DMSO)
$ 200.00
10 mg
$ 240.00
25 mg
$ 390.00
50 mg
$ 560.00
100 mg
$ 780.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry