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Kansuinine A

SKU: orb1297099

Description

Kansuinine A is a bioactive compound isolated from Euphorbia kansui roots. It inhibits IL-6-induced STAT3 activation via ERK1/2 pathway stimulation, making it a useful research tool for studying inflammation, cancer signaling, and autoimmune diseases in cellular models.

Research Area

Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number57701-86-7
MW730.75
Purity99.28%
FormulaC37H46O15
SMILES[H][C@]12O[C@](O)([C@H](C)C1=O)[C@]1(C[C@H](C)[C@H](OC(C)=O)[C@]1([H])[C@@H](OC(C)=O)C(=C)[C@H](OC(C)=O)[C@@H](OC(=O)c1ccccc1)[C@@H](OC(C)=O)C2(C)C)OC(C)=O
TargetIL Receptor,Interleukin,STAT
SolubilityDMSO:≥ 100 mg/mL (136.85 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.74 mM)

Bioactivity

In Vitro
Kansuinine A markedly promoted SPL proliferation and NO production by PMphi at concentrations from 0.78 to 12.50 microg/mL.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

IL Receptor, Inhibitor, Interleukin, Interleukin Related, Kansuinine A, inhibit, ILReceptor, IL-6, STAT3

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Key Properties

No computed properties available.

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Kansuinine A (orb1297099)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
$ 210.00
5 mg
$ 460.00
10 mg
$ 660.00
1 ml x 10 mM (in DMSO)
$ 710.00
25 mg
$ 1,020.00
50 mg
$ 1,360.00
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