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Kansuiphorin C

SKU: orb1297014

Description

Kansuiphorin C (KPC) is a bioactive natural product studied for its ability to ameliorate malignant ascites by modulating gut microbiota, notably increasing Lactobacillus and reducing Helicobacter. Research indicates it influences host carbohydrate and amino acid metabolism, supporting its investigation in oncology and gastroenterology for in vivo disease models.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number133898-77-8
MW478.58
Purity99.82%
FormulaC29H34O6
SMILES[H][C@@]12C[C@@H](C)[C@]34C=C(C)[C@H](OC(C)=O)[C@@]3(O)[C@H](OC(=O)c3ccccc3)C(C)=C[C@@]([H])(C4=O)[C@]1([H])C2(C)C
TargetAntibacterial,Others
SolubilityDMSO:30 mg/mL (62.69 mM)

Bioactivity

In Vivo
Kansuiphorin C(KPC) were modulatory compounds for gut microbiota. The richness of Lactobacillus and the decreased abundance of Helicobacter involved in the carbohydrate metabolism and amino acid metabolism could be responsible for their prohibitory effects on malignant ascites. KPC exhibited stronger modulation of gut microbiota through making the abundance of Helicobacter about 3.5 times lower than KA. Besides, in-vivo microbial biotransformation of Kansuiphorin C(KPC) contained oxidation, hydrolysis, dehydration, and methylation to form metabolites of lower polarity. Besides, at the dosage of 10 mg kg-1, the toxicity of both compounds had weaker influences on the gut microbiota of normal rats.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

KPC, Kansuiphorin C, inhibit, Inhibitor

Similar Products

  • Kansuiphorin C [orb1218914]

    >98% (HPLC)

    133898-77-8

    478.58

    C29H34O6

    10 mg, 1 g, 25 mg, 500 mg, 200 mg, 100 mg, 5 mg, 50 mg
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Key Properties

No computed properties available.

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Kansuiphorin C (orb1297014)

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Available Sizes

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1 mg
$ 110.00
5 mg
$ 210.00
1 ml x 10 mM (in DMSO)
$ 240.00
10 mg
$ 310.00
25 mg
$ 570.00
50 mg
$ 800.00
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