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Ketotifen

SKU: orb1744252

Description

Ketotifen (HC 20-511) is a second-generation, orally active, noncompetitive histamine 1 (H1) receptor antagonist and mast cell stabilizer. It inhibits 6-phosphogluconate dehydrogenase (PGD) in vitro and exhibits antiviral activity against SARS-CoV-2 and the Influenza virus. Ketotifen is also used in research on autoimmune encephalomyelitis (EAE) and in the prevention of asthma attacks.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number34580-13-7
MW309.43
FormulaC19H19NOS
SMILESO=C1C2=C(C(C=3C(C1)=CC=CC3)=C4CCN(C)CC4)C=CS2
TargetInfluenza Virus,Endogenous Metabolite,Histamine Receptor,SARS-CoV,Others

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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Ketotifen (orb1744252)

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