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Klotho-derived Peptide 1 (56-87) (human) TFA

SKU: orb1980033

Description

KP1 (Klotho-derived peptide 1 (56-87)) is a human Klotho fragment that inhibits TGF-β signaling by binding to TGFBR1/TGFBR2. It reduces fibrotic markers like fibronectin and α-SMA in vitro and ameliorates kidney injury and fibrosis in murine UUO and ischemia-reperfusion models, demonstrating therapeutic research potential for renal fibrosis.

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Key Properties

Molecular Weight3228.44

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Klotho-derived Peptide 1 (56-87) (human) TFA (orb1980033)

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