L-797,591 hydrochloride

SKU: orb1737827

Description

L-797,591 hydrochloride is a selective SSTR1 agonist used in pharmacological research. It is applied in vitro to study somatostatin receptor signaling, where it can induce p38 phosphorylation, an effect modulable by EGFR inhibitors like AG1478 in cellular models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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MW	644.30
Purity	98.65% (May vary between batches)
Formula	C₃₈H₅₀ClN₅O₂
SMILES	O=C(N(CCC1=CC=CC=N1)CCC2=CC=CC=C2)N[C@@H](C(NCC(C)(C)CC(C)CCN)=O)CC3=CC=CC4=C3C=CC=C4.Cl
Target	Somatostatin
Solubility	DMSO:55 mg/mL (85.36 mM)

Bioactivity

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In Vitro	L-797591 (10 nM; 1 h) reduced GLP-1-induced insulin secretion in RINm5F cells.

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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L-797,591 Hydrochloride, L-797,591 hydrochloride(217480-24-5 Free base), SST1

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Compound Identifiers

PubChem CID

169553403 ↗

Key Properties

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No computed properties available.

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