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L-803087 TFA

SKU: orb1984704

Description

L-803087 TFA is a highly potent and selective agonist of the somatostatin sst4 receptor, exhibiting a Ki value of 0.7 nM. It displays a remarkable selectivity, being over 280-fold more preferential for the sst4 receptor compared to other somatostatin receptors. Furthermore, L-803087 TFA promotes AMPA-mediated synaptic responses in hippocampal preparations and enhances kainate-induced seizures in mice.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1786412-46-1
MW599.55
FormulaC27H30F5N5O5
SMILESOC(=O)C(F)(F)F.COC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCc1c([nH]c2c(F)cc(F)cc12)-c1ccccc1
TargetOthers,Somatostatin

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

L-803087 TFA (orb1984704)

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