L-SelenoMethionine

SKU: orb1689898

Description

L-SelenoMethionine

Research Area

Cell Biology, Metabolism Research

Images & Validation

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Key Properties

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CAS Number	3211-76-5
MW	196.11
Purity	99.67%
Formula	C₅H₁₁NO₂Se
SMILES	[C@@H](C(O)=O)(CC[Se]C)N
Target	Apoptosis,Endogenous Metabolite,Amino Acids and Derivatives
Solubility	DMSO:< 1 mg/mL (insoluble or slightly soluble);H2O:27.5 mg/mL (140.23 mM)

Bioactivity

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In Vitro

At 5 μM, L-selenomethionine selectively induces apoptosis in LNCaP prostate cancer cells without affecting non-cancerous cells . c-Myc, cyclin C, proliferating cell nuclear antigen, cyclin-dependent kinase (cdk)1, cdk2, cdk4, cyclin B and cyclin D2 mRNA levels were lower in selenium-deficient cells than in the cells supplemented with 0.25 micromol/L selenomethionine. The phosphorylation state of total cellular protein was higher (57%) in selenium-supplemented cells than in selenium-deficient cells .

Storage & Handling

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Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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peroxidase, selenium, inhibit, L-(+)-Selenomethionine, L SelenoMethionine, L-SelenoMethionine, LSelenoMethionine, Inhibitor, Endogenous Metabolite, EndogenousMetabolite, glutathione, dietary, chemopreventive, cancer, Amino Acids and Derivatives, AminoAcidsandDerivatives, Apoptosis

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Compound Identifiers

PubChem CID

105024 ↗

Key Properties

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No computed properties available.

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