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Lamivudine triphosphate

SKU: orb2664540

Description

Lamivudine triphosphate (3TCTP), a phosphorylated form of the nucleoside analogue Lamivudine, inhibits the reverse transcriptase of HIV or HBV, blocking viral replication through chain termination. It also acts as an inhibitor of the RdRp activity of the HCVNS5B subunit. Additionally, Lamivudine triphosphate can be incorporated into nascent RNA by SARS-CoV-2 RdRp, thereby preventing mutations in the newly synthesized SARS-CoV-2 RNA.

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Key Properties

CAS Number143188-53-8
MW469.2
FormulaC8H14N3O12P3S
SMILESO=C1N(C=CC(N)=N1)[C@H]2O[C@@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)SC2

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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Lamivudine triphosphate (orb2664540)

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