Ledipasvir (acetone)

SKU: orb1303066

Description

Ledipasvir (acetone), also known as GS-5885 acetone, is a potent and selective inhibitor of the hepatitis C virus (HCV) NS5A protein. It is widely used in both in vitro and in vivo research to study HCV replication mechanisms and evaluate potential antiviral therapies for chronic hepatitis C infection.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Images & Validation

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Key Properties

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CAS Number	1441674-54-9
MW	947.08
Purity	100.00%
Formula	C₅₂H₆₀F₂N₈O₇
SMILES	CC(C)=O.[H][C@]12CC[C@]([H])(C1)N([C@@H]2c1nc2ccc(cc2[nH]1)-c1ccc2-c3ccc(cc3C(F)(F)c2c1)-c1cnc([nH]1)[C@@H]1CC2(CC2)CN1C(=O)[C@@H](NC(=O)OC)C(C)C)C(=O)[C@@H](NC(=O)OC)C(C)C
Target	HCV Protease
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (4.22 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:100 mg/mL (105.59 mM);Ethanol:100 mg/mL (105.59 mM)

Bioactivity

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Target IC50	GT1a:34 pM (EC50)\|GT1b:4 pM(EC50)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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acetone, GS-5885 acetone, HCV, HCV Protease, HCVProtease, Hepatitis C virus, Ledipasvir, Ledipasvir (acetone), Ledipasvir acetone, inhibit, Inhibitor

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Compound Identifiers

PubChem CID

78357793 ↗

Key Properties

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No computed properties available.

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