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Ledipasvir

SKU: orb1223362

Description

Ledipasvir, also known as GS-5885; is an inhibitor of the hepatitis C virus NS5A protein and is a drug for the treatment of hepatitis C that was developed by Gilead Sciences. On October 10, 2014 the FDA approved the combination product ledipasvir 90 mg/sofosbuvir 400 mg (trade name Harvoni). The ledipasvir/sofosbuvir combination is a direct-acting antiviral agent that interferes with HCV replication and can be used to treat patients with genotypes 1a or 1b without PEG-interferon or ribavirin.

Images & Validation

Key Properties

CAS Number1256388-51-8
MW889
Purity>98% (HPLC)
FormulaC49H54F2N8O6
SMILESO=C(OC)N[C@H](C(=O)N1[C@H](c2ncc(c3cc4C(F)(F)c5c(ccc(c6ccc7nc([C@H]8N(C(=O)[C@@H](NC(=O)OC)C(C)C)[C@@H]9CC[C@H]8C9)[nH]c7c6)c5)c4cc3)[nH]2)CC2(C1)CC2)C(C)C
TargetHDAC
SolubilityDMSO : 50 mg/mL. 56.24 mM;H2O : < 0.1 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GS5885 | GS-5885 | GS 5885 | Ledipasvir

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Protocol Information

Ledipasvir (orb1223362)

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% DMSO +
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% Tween 80 +
%

Available Sizes

Select a size below

2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 150.00
25 mg
$ 240.00
50 mg
$ 380.00
100 mg
$ 630.00
500 mg
$ 1,400.00