Lenalidomide-C4-NH2 hydrochloride

SKU: orb1988414

Description

Lenalidomide-C4-NH2 hydrochloride is a Cereblon (CRBN)-binding ligand used to construct PROTAC degraders. This recruiting moiety, exemplified in compounds like PROTAC 24, has demonstrated potent in vitro anti-proliferative activity in acute leukemia cell models such as RS4;11 and MOLM-13.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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MW	351.83
Formula	C₁₇H₂₂ClN₃O₃
SMILES	O=C(C(N(CC1=C2C=CC=C1CCCCN)C2=O)CC3)NC3=O.Cl
Target	PROTAC Linker,Others,E3 Ligase Ligand-Linker Conjugates

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

138377587 ↗

Key Properties

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No computed properties available.

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