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Leucosceptoside A

SKU: orb1682217

Description

Leucosceptoside A, a natural compound isolated from Oroxylum indicum bark, exhibits antidiabetic and antihypertensive properties. Research demonstrates its ability to modulate psoriasis-like inflammation through in vitro inhibition of the PI3K/AKT pathway in keratinocytes, supporting its study in dermatological and metabolic research.

Research Area

Epigenetics & Chromatin, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number83529-62-8
MW638.61
Purity99.78% (May vary between batches)
FormulaC30H38O15
SMILESO([C@H]1[C@H](OC(/C=C/C2=CC(OC)=C(O)C=C2)=O)[C@@H](CO)O[C@@H](OCCC3=CC(O)=C(O)C=C3)[C@@H]1O)[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4
TargetGlucosidase,glycosidase,PKC,Angiotensin-converting Enzyme (ACE)

Bioactivity

Target IC50
PKCα:19 μM (IC50)
In Vitro
Leucosceptoside A regulates psoriatic-like inflammation by inhibiting the PI3K/AKT signaling pathway in keratinocytes. Leucosceptoside A had no inhibitory effect on hyaluronidase.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ACE, Leucosceptoside A, PKC
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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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5 mg
$ 340.00
DispatchUsually dispatched within 5-10 working days
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