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Leucylarginylproline

SKU: orb1220310

Description

Leucylarginylproline is an inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM).

Images & Validation

Key Properties

CAS Number133943-59-6
MW384.47
Purity>98% (HPLC)
FormulaC17H32N6O4
SMILESCC(C)CC(N)C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)O
TargetRAAS

Bioactivity

In Vitro
Intravenous injection of Leucylarginylproline (30 mg/kg) causes a decrease in the blood pressure. The maximum mean blood pressure reduction (about 15 mmHg) occurrs about 2 min after the injection. Leucylarginylproline peptide reduces the blood pressure by about 15 mmHg at the fourth hour and shows a maximal reduction effect of about 35 mmHg at the eighth hour after oral administration.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Leucylarginylproline (orb1220310)

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200 mg
500 mg
5 mg
$ 540.00
10 mg
$ 800.00
25 mg
$ 1,180.00
50 mg
$ 1,740.00
100 mg
$ 2,350.00