Levalbuterol tartrate

SKU: orb1224308

Description

A short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).Asthma Approved(In Vitro):Levalbuterol (10 μM; 24 hours) hydrochloride induces 11β-HSD1 mRNA expression, however, it does not influence 11β-HSD2expression in airway epithelial cells.Levalbuterol (10 μM; 24 hours) hydrochloride significantly reduces both LPS- and TNF-α-induced NF-κB activity while increasing GRE activation in an 11β-HSD1 dependent manner in a transformed mouse airway epithelial cell line.(In Vivo):Levalbuterol (subcutaneous injection; 1 mg/kg; 14 days) hydrochloride significantly decreases pulmonary inflammation in OVA mice, demonstrated a decrease in eosinophilia and IgE.

Images & Validation

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Key Properties

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CAS Number	661464-94-4
MW	628.7083
Purity	>98% (HPLC)
Formula	C₃₀H₄₈N₂O₁₂
SMILES	CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O.C(C(C(=O)O)O)(C(=O)O)O
Target	Adrenergic Receptor
Solubility	10 mM in DMSO

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Levosalbutamol tartrate

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Gene Symbol

Adrenergic Receptor

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