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(-)-Licarin B

SKU: orb1222142

Description

Licarin B is a neolignan isolated from seeds of Myristica fragrans.

Images & Validation

Key Properties

CAS Number51020-87-2
MW324.37
Purity>98% (HPLC)
FormulaC20H20O4
SMILESCC=CC1=CC2=C(C(=C1)OC)OC(C2C)C3=CC4=C(C=C3)OCO4
Targetanti-mycobacterial
SolubilityIn Vitro: DMSO : 100 mg/mL (308.29 mM)

Bioactivity

In Vitro
Licarin B (5 μM, 10 μM, 15 μM. 8 days) moderately increases TG accumulation during adipogenic differentiation and showed partial PPARg agonist activity in 3T3-L1 preadipocytes. Cell Viability Assay Cell line: 3T3-L1 cell. Concentration: 1-500 μM. Incubation time: 48 h. Result: Did not cause significant cell death up to 500 μM concentration. Cell Viability Assay Cell line: 3T3-L1 cell. Concentration: 5 μM, 10 μM, 15 μM. Incubation time: 8 days (replaced every 2 days). Result: LB at 15 μM concentration significantly promoted adipocyte differentiation and caused intracellular TG accumulation.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Licarin B

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(-)-Licarin B (orb1222142)

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% DMSO +
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200 mg
500 mg
5 mg
$ 120.00
10 mg
$ 170.00
25 mg
$ 270.00
50 mg
$ 380.00
100 mg
$ 550.00