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Lilotomab Antibody

SKU: orb1980381

Description

Lilotomab (HH1) is a murine monoclonal antibody targeting CD37. Its radiolabeled conjugate, ¹⁷⁷Lu-lilotomab satetraxetan, is a synthetic radioimmunotherapeutic agent used in preclinical research for targeting B-cell malignancies in both in vitro and in vivo experimental models.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number1453362-55-4
MW145.23 kDa
Purity95.00%
TargetApoptosis

Bioactivity

In Vivo
In a mouse model, Lilotomab (0.5 mg/kg, i.v., single dose) effectively inhibited tumor growth.
In Vitro
Lilotomab (0-40 µg/mL, treated for 12 days) significantly reduced clone formation survival of DOHH2 and Ramos cells. Lilotomab (40 µg/mL, 18 hours of treatment) produced mild apoptotic effects on DOHH2 cells.

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

apoptosis, HH1

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Protocol Information

Lilotomab Antibody (orb1980381)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
$ 310.00
5 mg
$ 770.00
10 mg
$ 1,030.00
25 mg
$ 1,530.00
DispatchUsually dispatched within 5-10 working days
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