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Lipid 88

SKU: orb3033115

Description

Lipid88​​ is a high-performance, novel ionizable lipid component engineered for advanced mRNA-LNP vaccine delivery. LNP88 formulation demonstrates superior biodistribution, achieving >10-fold higher transfection efficiency in spleen and lymph nodes compared to benchmark lipids like ALC-0315 via intramuscular delivery. When encapsulating antigen-encoding mRNA (e.g., optimized mCSA construct), Lipid-88 based LNPs drive robust humoral and cellular immunity, enabling complete protection against challenging SARS-CoV-2 variants (WA1/2020, Omicron BA.1, BQ.1) in preclinical models. Its design prioritizes potent immunogenicity with favorable safety profiles.

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Key Properties

CAS Number2982842-99-7
MW1459
Purity>98%
FormulaC79H147N3O20
SMILESCCCCCCC(CCCC)COC(OCCOC(CCN(CCC(OCCOC(OCC(CCCC)CCCCCC)=O)=O)CCCN(C)CCCN(CCC(OCCOC(OCC(CCCC)CCCCCC)=O)=O)CCC(OCCOC(OCC(CCCC)CCCCCC)=O)=O)=O)=O

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Lipid 88 (orb3033115)

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100 mg
25 mg
$ 700.00
50 mg
$ 1,200.00