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Loratadine

SKU: orb1223983

Description

A tricyclic antihistamine that acts as a selective inverse agonist of peripheral histamine H1-receptors.Allergy Approved(In Vitro):Loratadine is an antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.

Images & Validation

Key Properties

CAS Number79794-75-5
MW382.8832
Purity>98% (HPLC)
FormulaC22H23ClN2O2
SMILESCCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1
TargetHistamine Receptor
Solubility10 mM in DMSO

Bioactivity

In Vitro
Loratadine is an antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Loratidine | SCH-29851

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Loratadine (orb1223983)

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