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LXR agonist 4

SKU: orb3174467

Description

LXR agonist4 is a selective LXR inverse agonist, with IC50 values of 7.6 μM for LXRα and 2.9 μM for LXRβ. It exhibits selectivity for RORα and FXR. Additionally, LXR agonist4 markedly inhibits the expression of SREBP1c without affecting the expression of ABCA1 or APOE. It possesses anti-lipogenic properties and can prevent fat accumulation induced by fatty acids. This compound is useful for research in atherosclerosis and metabolic dysfunction-associated steatotic liver disease (MASLD).

Research Area

Metabolism Research

Images & Validation

Key Properties

TargetLiver X Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information