LXR beta agonist 17

SKU: orb692006

Description

LXRβ agonist 17 is a novel, potent, orally active liver X receptor β (LXRβ) agonist with Ki/EC50 of 3/21 nM, displays 27-fold selectivity over LXRα; also exhibits excellent selectivity against other nuclear hormone receptors (>3,000-fold); induces the expression of LXR target genes in vitro and in vivo.

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Key Properties

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CAS Number	1878259-00-7
MW	488.52369427681
Formula	C₂₁H₂₇F₃N₄O₄S
SMILES	S(C)(C1=C(CO)C=CC(=C1)N1CCN(C2N=CC(CO)=C(C(F)(F)F)N=2)[C@H](C(C)C)C1)(=O)=O

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Disclaimer	For research use only

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