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LY2623091

SKU: orb2564485

Description

LY2623091 is a mineralocorticoid receptor antagonist used in research for resistant hypertension. Its clearance is mediated by CYP3A4, and its pharmacokinetics are significantly altered by co-administration with CYP3A4 inhibitors. This compound is a tool for investigating hypertension mechanisms in both in vitro binding assays and in vivo animal models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1162264-07-4
MW527.59
FormulaC30H30FN5O3
SMILESC(=C\1/C=2C(OCC=3C1=CC=CC3)=CC(F)=CC2)\C=4C=C5C(=CC4)N([C@@H](CN6CCOCC6)C)C(NC(N)=O)=N5
TargetGlucocorticoid Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

LY2623091 (orb2564485)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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