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Mahanine

SKU: orb1680544

Description

Mahanine is a natural alkaloid that induces apoptosis in leukemia U937 cells via mitochondrial membrane permeabilization and caspase-3 activation. It also acts as an epigenetic modulator in prostate cancer by inhibiting DNMT activity, leading to RASSF1A reactivation and cyclin D1 downregulation, highlighting its potential for cancer research.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number28360-49-8
MW347.458
FormulaC23H25NO2
SMILESCC(C)=CCC[C@@]1(C)Oc2c(C)cc3c([nH]c4cc(O)ccc34)c2C=C1 |wU:6.6,wD:6.5,c:27,(12.99,-4.96,;11.75,-4.04,;10.34,-4.65,;11.93,-2.51,;10.7,-1.59,;10.88,-.06,;9.65,.86,;10.77,1.91,;8.8,2.15,;7.26,2.06,;6.42,3.35,;7.11,4.72,;4.88,3.26,;4.19,1.88,;5.03,.59,;4.07,-.61,;2.63,-.06,;1.26,-.77,;-.04,.06,;-1.4,-.64,;.04,1.6,;1.41,2.31,;2.7,1.48,;6.57,.68,;7.42,-.61,;8.95,-.52,)|
TargetParasite

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Mahanine (orb1680544)

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