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Recombinant Mammaglobin Antibody / SCGB2A2

SKU: orb2642534

Description

Mammaglobin, also called Secretoglobin family 2A member 2, or SCGB2A2, is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues. Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.

Images & Validation

Tested ApplicationsIHC-P
Dilution RangeThe prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
ReactivityHuman
Application Notes
Optimal dilution of the recombinant Mammaglobin antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Key Properties

Antibody TypePrimary Antibody
HostRabbit
ClonalityRecombinant
IsotypeRabbit IgG, kappa
Clone No.MGB/2682R
ImmunogenFull length recombinant human protein was used as the immunogen for the recombinant Mammaglobin antibody.
PurificationProtein A affinity chromatography
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/PreservativesPrediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Recombinant Mammaglobin Antibody / SCGB2A2

IHC testing of FFPE human breast carcinoma stained with recombinant Mammaglobin antibody (clone MGB/2682R). Required HIER: boiling tissue sections in 10 mM citrate buffer, pH6, for 10-20 min followed by cooling at RT for 20 min.

Recombinant Mammaglobin Antibody / SCGB2A2

IHC testing of FFPE human breast carcinoma stained with recombinant Mammaglobin antibody (clone MGB/2682R). Required HIER: boiling tissue sections in 10 mM citrate buffer, pH6, for 10-20 min followed by cooling at RT for 20 min.

Recombinant Mammaglobin Antibody / SCGB2A2

SDS-PAGE analysis of purified, BSA-free recombinant Mammaglobin antibody (clone MGB/2682R) as confirmation of integrity and purity.

UniProt Details

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Protocol Information

IHC-P
Immunohistochemistry Paraffin
View Protocol

Recombinant Mammaglobin Antibody / SCGB2A2 (orb2642534)

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7 ml
$ 750.00
DispatchUsually dispatched within 5-10 working days
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