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MC-Val-Cit-PAB

SKU: orb1221313

Description

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number159857-80-4
MW572.65
Purity>98% (HPLC)
FormulaC28H40N6O7
SMILESCC(C)[C@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
TargetOthers
SolubilityDMSO:≥ 22 mg/mL (38.42 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

MC-Val-Cit-PAB (orb1221313)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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