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Mc-VC-PAB-SN38

SKU: orb1691475

Description

Mc-VC-PAB-SN38 is a cleavable linker-payload conjugate used in the synthesis of antibody-drug conjugates (ADCs). This construct enables targeted delivery of the potent topoisomerase I inhibitor SN38, facilitating research into ADC efficacy and mechanism in both in vitro and in vivo cancer models.

Images & Validation

Key Properties

CAS Number1801838-28-7
MW991.05
Purity99.22% (May vary between batches)
FormulaC51H58N8O13
SMILESCCc1c2Cn3c(cc4c(COC(=O)[C@@]4(CC)OC(=O)OCc4ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN5C(=O)C=CC5=O)C(C)C)cc4)c3=O)-c2nc2ccc(O)cc12
TargetDrug-Linker Conjugates for ADC
SolubilityDMSO:50 mg/mL (50.45 mM)

Bioactivity

In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DrugLinkerConjugatesforADC, DrugLinker Conjugates for ADC, Antibody-Drug Conjugates (ADCs), Mc VC PAB SN38, McVCPABSN38, Mc-VC-PAB-SN38, Mc-VC-PAB-SN-38

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 240.00
5 mg
$ 530.00
10 mg
$ 780.00
25 mg
$ 1,130.00
50 mg
$ 1,520.00
100 mg
$ 2,020.00
200 mg
$ 2,770.00
DispatchUsually dispatched within 5-10 working days
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