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MCB-22-174

SKU: orb3027391

Description

MCB-22-174 is a potent agonist of Piezo1 with an EC50 value of 6.28 µM. It activates Ca2+-related extracellular signal-regulated kinase and calcium-calmodulin (CaM)-dependent protein kinase II (CaMKII) pathways, and it promotes mesenchymal stem cell osteogenic differentiation, indicating its potential application in the study of disuse osteoporosis (OP).

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Key Properties

CAS Number3058199-58-6
MW429.37
FormulaC16H14DCl2N5OS2
SMILESS(C(C1=C(Cl)C=CC=C1Cl)[2H])C=2SC(=NN2)C=3C=NC(NC[C@@H](C)O)=CN3
TargetOthers

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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MCB-22-174 (orb3027391)

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