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Mefenamic acid

SKU: orb1310196

Description

Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) that acts as a cyclooxygenase (COX) inhibitor. It is widely used in research for its analgesic and antipyretic properties, applicable in both in vitro enzyme assays and in vivo models of inflammation and pain.

Research Area

Immunology & Inflammation, Neuroscience

Images & Validation

Key Properties

CAS Number61-68-7
MW241.29
Purity99.85% (May vary between batches)
FormulaC15H15NO2
SMILESCC1=C(C)C(NC2=C(C=CC=C2)C(O)=O)=CC=C1
TargetCOX
SolubilityDMSO:100 mg/mL (414.44 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:20 mg/mL (82.89 mM)

Bioactivity

Target IC50
COX-1 (human):40 nM|COX-2 (human):3 μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

COX, CN35355, CN-35355, CN 35355, CI 473, CI473, CI-473, Cyclooxygenase, COX-1, COX-2, inhibit, Inhibitor, Mefenamic acid

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Key Properties

No computed properties available.

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Mefenamic acid (orb1310196)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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200 mg
$ 80.00
500 mg
$ 90.00
1 g
$ 100.00
1 ml x 10 mM (in DMSO)
$ 100.00
5 g
$ 130.00
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