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Menthone

SKU: orb1301609

Description

Menthone

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction

Images & Validation

Key Properties

CAS Number10458-14-7
MW154.25
Purity97.02%
FormulaC10H18O
SMILESCC(C)C1CCC(C)CC1=O
TargetNF-κB,Parasite,TNF,IL Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (12.97 mM);DMSO:30 mg/mL (194.49 mM)

Bioactivity

In Vivo
Menthone and Vit C at higher dose have a good compensatory effect with significant reduction in DNA damages in sperm cells by reversing the adverse effect of ACV on the reproductive system in male rat.
Animal Research
Adult male albino Wistar rats with average weight of 250±10 gr, were divided into six groups (n=18/each), as: ACV (15 mg/kg/day), ACV+Vit C (20 mg/kg/day), ACV+ menthone (100 μl/d), ACV+ menthone (250 μl/d), ACV+ menthone (400 μl/day) and control group without any treatment. At the end of experiment, the animals were sacrificed and sperm samples were collected and isolated in phosphate-buffered saline and examined by TUNEL staining process. The percentage of TUNEL positive spermatozoa was evaluated by fluorescence microscopy. Each experiment was performed in three repeats

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

antioxidant, anti-Inflammatory, Parasite, NF-κB, NFkB, NF-kB, NFκB, inhibit, ILReceptor, IL receptor, IL Receptor, Menthone, Inhibitor, TNF-α, volatile

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Key Properties

No computed properties available.

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Menthone (orb1301609)

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1 ml x 10 mM (in DMSO)
$ 70.00
500 mg
$ 70.00
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