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MKP10241

SKU: orb3173012

Description

MKP10241 is an orally bioavailable GPR119 agonist that increases cAMP levels in GPR119-expressing cell lines with an EC₅₀ of 3.7 nM. It significantly reduces blood glucose and glycated hemoglobin (HbA1c) levels in acute and chronic diabetic mouse models. It also exhibits favorable pharmacological activities in acute and chronic obesity models and MASH rodent models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2137977-29-6
MW530.64
Purity99.79% (May vary between batches)
FormulaC24H27FN6O3S2
SMILESFC1=C(C2=CN3C(=N2)SC(O[C@@H](C)C4CCN(CC4)C=5N=CC(CC)=CN5)=N3)C=CC(S(C)(=O)=O)=C1
TargetGPCR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information

Available Sizes

Select a size below

1 mg
$ 240.00
5 mg
$ 570.00
1 ml x 10 mM (in DMSO)
$ 640.00
10 mg
$ 880.00
25 mg
$ 1,710.00
50 mg
$ 2,720.00
DispatchUsually dispatched within 5-10 working days
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