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ML-20

SKU: orb3135457

Description

ML-20, an analog of Malabaricone C, functions as both an autophagy inhibitor and a radiosensitizer. It suppresses cell proliferation and induces apoptosis (cell death). ML-20 also causes DNA double-strand breaks, loss of mitochondrial membrane potential (MMP), and lysosomal membrane permeabilization (LMP). Due to LMP, it triggers endoplasmic reticulum stress while concurrently inhibiting autophagic flux.

Images & Validation

Key Properties

TargetApoptosis,Autophagy

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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ML-20 (orb3135457)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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