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ML-T7

SKU: orb2565773

Description

ML-T7 is a potent Tim-3 inhibitor that blocks interactions with PtdSer and CEACAM1. It enhances the antitumor function of CTLs, CAR T cells, and NK cells in vitro and improves dendritic cell antigen presentation. This compound demonstrates efficacy in preclinical tumor models, supporting its investigation as a monotherapy or combined with checkpoint inhibitors like Nivolumab.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number459789-75-4
MW506.33
FormulaC27H17Cl2NO5
SMILESO=C1C2(C3C(C(O2)C4=CC=C(C)C=C4)C(=O)N(C3=O)C5=C(Cl)C=C(Cl)C=C5)C(=O)C=6C1=CC=CC6
TargetImmunology/Inflammation related

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

ML-T7 (orb2565773)

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